Initial Human Herpesvirus–8 Rash and Multicentric Castleman Disease

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Initial human herpesvirus-8 rash and multicentric Castleman disease.

We describe a human immunodeficiency virus-infected man with relapsing rashes and reactivation of human herpesvirus-8 (HHV-8) infection, which evolved into multicentric Castleman disease. Initial skin biopsy revealed infiltrating HHV-8-positive plasmablasts, a subset of which supported lytic infection. We document the first case, to our knowledge, of HHV-8-induced rash and suggest that circulat...

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ژورنال

عنوان ژورنال: Clinical Infectious Diseases

سال: 2008

ISSN: 1058-4838,1537-6591

DOI: 10.1086/590942